Number of cases campus Landau: 1 (warning level Gelb until 01.02.2021) Action plan

Expectation-focused psychological interventions (EFPI) to optimize treatment of major depression

Period: Jan 22, 2021 - Jan 22, 2021
Status: laufend

In this project, we aim to evaluate an expectation-focused approach to optimize treatment of patients with major depression. In particular, we are developing a structured cognitive-behavioral therapy program that aims to modify patients’ dysfunctional expectations. Previous research examining patients with anxiety disorders has shown that expectations can effectively modified if patients are exposed to situations where it is likely for them to gain experiences that disconfirm their expectations (“expectancy violation”). Given these promising findings, we aim to transfer this novel treatment approach to the treatment of major depression. In particular, we are testing different therapeutic strategies to prevent patients from engaging in cognitive immunization strategies, thus maximizing expectation change. Furthermore, we are planning to examine differential treatment effects among patients with chronic vs. episodic depressive disorders.

Project partner

Prof. Dr. Winfried Rief, University of Marburg


University of Marburg Research Funds


Ostbahnstraße 10 (3. OG, 3.1.06); 76829 Landau
+49 6341 280-35652
kube at
Ostbahnstr. 10 (3. OG, 3.1.11), 76829 Landau
+49 6341 280-35645
glombiewski at



Doering, B.K, Glombiewski, J.A., Rief W. (2018). Expectation-Focused Psychotherapy to Improve Clinical Outcomes. International Review Neurobiology, 138:257-270.

Kube, T., Rief, W., Gollwitzer, M., & Glombiewski, J. A. (2018). Introducing an EXperimental Paradigm to investigate Expectation Change (EXPEC). Journal of Behavior Therapy and Experimental Psychiatry, 59, 92-99

Rief, W. & Glombiewski, J.A. (2017). The role of expectations in mental disorders and their treatment. World Psychiatry, 16(2), 210-211.

Rief, W., & Glombiewski, J. A. (2016). Expectation-Focused Psychological Interventions (EFPI). Verhaltenstherapie, 2016(26), 47-54.